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Challenge to The Limits of Life
Laboratory of Biochemistry
Yoshihisa Hirota
Assistant Professor, Department of Bioscience and Engineering
College of Systems Engineering and Science
Systems Engineering and Science in Master's Program
Functional Control Systems in Doctoral Program
Location: Omiya Campus
Laboratory Overview
Understand the essence of life phenomena through research!
Japanese people eat natto from the usual. This natto contains a lot of vitamin K. The details of how vitamin K is used in vivo so far have not been clarified. Our laboratory is conducting analysis of the in vivo metabolic mechanism of lipid soluble vitamins, mainly vitamin K, by using molecular biological methods. We also evaluate the role of fat-soluble vitamins on age-related diseases such as osteoporosis and Alzheimer's disease.
Laboratory Character Research on vitamins is one of the leading Japanese studies. Vitamins exhibit a very small amount and strong physiological activity, indispensable to living bodies. Our laboratory focuses on lipid-soluble vitamins and searches for unknown effects of vitamins and conducts drug discovery research using vitamin skeletons.
Research Outputs You can review research papers in the website below.
Laboratory Research Field
Vitamin K Vitamin D Fat-soluble vitamin Biological metabolism Bone metabolism
Nervous development Polyphenol Drug discovery    
Recent Research Topics
Elucidation of biological metabolism mechanism of vitamin K Neuronal differentiation by vitamin K Analysis of intracellular uptake mechanism of platinum preparations    
Affiliated Conferences
The Pharmaceutical Society of Japan Vitamin Society of Japan The Japanese Biochemical Society The Molecular Biology Society of Japan Japanese Society for Food Factors
For Social Contributions to the World Sustainability By studying and mastering biochemical approaches from cell culture to animal experiments, you can expect to be active in the life sciences fields of pharmaceutical companies and food companies.
Related Industries
Researchers educators medical personnel    
Applicable Industrial Fields
Pharmacy Life Sciences Food and Nutrition    
Instruments and Devices in this Laboratory
Real-time PCR fluorescence plate reader microspectrophotometer chemiluminescent (western blot) detector fluorescence microscope
Research Seeds
Derivatives of Vitamin K Vitamin D Polyphenol